Neutralization of Omicron sublineages and Deltacron SARS-CoV-2 by three doses of BNT162b2 vaccine or BA.1 infection3회분의 BNT162b2 백신 또는 BA.1 감염에 의한 Omicron 하위 계통 및 Deltacron SARS-CoV-2 중화Article Published on 2022-12-012022-09-11 Journal: Emerging Microbes & Infections [Category] COVID19(2023년), SARS, 변종, 임상, 진단, [키워드] Antibody neutralization BNT162b2 BNT162b2 vaccine contribute convalescent sera dose evade geometric mean geometric mean titre geometric mean titres GMT GMTs highest Identifier immune immune evasion individual infected individual infected individuals Infection Mutation neutralization neutralization activity neutralized of BNT162b2 omicron post-dose SARS-CoV-2 SARS-CoV-2 spike sera titre Trial registration unique USA-WA1/2020 vaccinated individual Vaccine variant variants variants. [DOI] 10.1080/22221751.2022.2099305 PMC 바로가기 [Article Type] Article
Temporal dynamics of SARS-CoV-2 genome and detection of variants of concern in wastewater influent from two metropolitan areas in ArkansasArticle Published on 2022-11-252022-11-15 Journal: The Science of the total environment [Category] COVID19(2023년), SARS, 변종, 치료기술, 치료제, [키워드] Affect approach Arkansas association Asymptomatic changes in Community complementary contribute coronavirus COVID-19 COVID-19 case COVID-19 testing death detect diagnostic Factors fecal genetic diversity Genetic variant genomic change highlight identity infected individual investigated nucleocapsid ORF1ab polymerase chain polyprotein public health quantified Quantitative recorded RNA sequencing RT-qPCR RT-qPCR assay SARS-CoV-2 SARS-CoV-2 genome SARS-CoV-2 mutations SARS-CoV-2 RNA SARS-CoV-2 variant sensitivity silent Support Surface glycoprotein Surveillance TaqMan assay target Temporal the disease transmission of SARS-CoV-2 variants variants of concern viral gene viral titer virus virus genome was used wastewater Wastewater. [DOI] 10.1016/j.scitotenv.2022.157546 PMC 바로가기
IgG-RBD Response Due to Inactivated SARS-CoV-2 Vaccine: Alteration in D-Dimer and Fibrinogen Concentrations, Association with Comorbidities and Adverse EffectsArticle Published on 2022-11-032022-11-15 Journal: Laboratory medicine [Category] SARS, 진단, [키워드] Adverse alteration appear blood sample both groups changes in Concentration CoronaVac Coronavirus infection COVID-19 COVID-19 infection D-dimer D-dimer level domain Effect effective fibrinogen fibrinogen level first vaccination IgG Immunoglobulin individual infected individual Infection Mask Measures Participants Protective response Safe SARS-CoV-2 second dose second vaccination Side effects significantly higher statistically subject vaccination vaccination. Vaccine was obtained were measured [DOI] 10.1093/labmed/lmac047 PMC 바로가기
Mortality and Deep Vein Thrombosis in the Gamma Variant of Covid 19 and Lung InjuryArticle Published on 2022-11-032022-11-16 Journal: Vascular Health and Risk Management [Category] SARS, 변종, [키워드] affecting Analysis chi-square test clinical suspicion Coagulation complications conducted COVID-19 Critically ill patient deep Deep vein Deep vein thrombosis determine DVT Factor Fisher Gamma greater had more hospital infected individual inhibitor intensive care involved lesion less lung mechanism medical record Mortality occurred Patient patients with SARS-CoV-2 positive Prevalence pulmonary pulmonary injury Pulmonary thrombosis. Retrospective study SARS-CoV-2 disease severe lung injury t -test thrombosis thrombotic event Treatment two group variant Vein Venous thrombosis [DOI] 10.2147/VHRM.S367930 PMC 바로가기
Systematic review and meta-analysis of human genetic variants contributing to COVID-19 susceptibility and severityReview article Published on 2022-11-012022-10-05 Journal: Gene [Category] SARS, 바이오마커, 변종, 유전자 메커니즘, [키워드] ACE1 ACE2 AGTR1 ApoE association Case-control CCR5 Clinical outcome contribute contributing to Control correlation country COVID-19 COVID-19 pandemic COVID-19 susceptibility Critical eligible Evidence exacerbated examined Factor Genes Genetic genetic determinant Genetic polymorphism Genetic variant greater Health Healthcare system Host host genetics human gene I/D identify IFITM3 implicated increased risk increasingly infected individual infected individuals Infection investigated magnitude manifestation Manifestations Meta-analysis meta-analysis mutations Patient performed polymorphism progression provide required Research rs2285666 SARS-CoV-2 severe COVID-19 severity Statistical power statistically significant susceptibility systematic review variant with COVID-19 [DOI] 10.1016/j.gene.2022.146790 [Article Type] Review article
Pronounced antibody elevation after SARS-CoV-2 BNT162b2 mRNA booster vaccination in nursing home residentsArticle Published on 2022-11-012022-11-15 Journal: Influenza and Other Respiratory Viruses [Category] SARS, 진단, [키워드] age Anti-spike antibody Antibody Response BNT162b2 mRNA vaccination booster booster dose booster vaccination changed characterized COVID-19 COVID-19 outbreak Critical domain dose evaluated Factor four groups groups healthcare healthcare worker highest IgG infected individual initial lowest median mRNA nursing home residents. public health RBD Responder SARS-CoV-2 SARS-CoV-2 BNT162b2 SARS-CoV-2 vaccination SARS-CoV-2 vaccine second dose significantly higher vaccination [DOI] 10.1111/irv.13030 PMC 바로가기
Antibody correlates of protection from SARS-CoV-2 reinfection prior to vaccination: A nested case-control within the SIREN studyArticle Published on 2022-11-012022-11-15 Journal: The Journal of Infection [Category] SARS, 진단, 치료기술, [키워드] age analysed anti-S anti-SARS-CoV-2 antibody association Case-control case-control study controls correlated fixed Gender identify Immunity Increasing infected individual Infection Linear regression Live virus logistic regression models Neutralising Antibodies no difference nucleocapsid occurred performed pre-vaccination protective effect pseudovirus reduced risk Reinfection required Result SARS-CoV-2 SARS-CoV-2 serology. serological serology serum sample significantly lower SIREN study tested titre titres vaccination Wuhan [DOI] 10.1016/j.jinf.2022.09.004 PMC 바로가기
An external quality assessment for the molecular testing of the SARS-CoV-2 virus genome in Zhejiang Province, ChinaArticle Published on 2022-11-012022-11-15 Journal: Diagnostic microbiology and infectious disease [Category] COVID19(2023년), SARS, 진단, [키워드] Accuracy Asymptomatic CDC China Combination Concentration concentrations Concordance COVID-19 COVID-19 pandemic Culture diagnostics external quality assessment false-negative False-positive Genome infected individual Laboratory medium molecular molecular diagnostics. negative sample nucleic acid extraction organized participated PCR Population positive sample provide public health rapid expansion reagents SARS-CoV-2 SARS-CoV-2 test SARS-CoV-2 tests serial dilution the SARS-CoV-2 virus viral titer Zhejiang [DOI] 10.1016/j.diagmicrobio.2022.115766 PMC 바로가기
Public acceptance of COVID-19 vaccination among residents of Saudi Arabia: a cross-sectional online studyArticle Published on 2022-10-312022-11-15 Journal: BMJ Open [Category] 치료제, [키워드] Arabic Complete conducted COVID-19 COVID-19 pandemic COVID-19 vaccination COVID-19 vaccine cross-sectional detect Factor form Google Healthcare system highest immunology inclusion criteria infected individual less Logistic regression analysis men number Older Pandemics participant platform Public public health public health. Research Saudi Arabia Saudi riyal selected shown the vaccine vaccination variable viral infection was used [DOI] 10.1136/bmjopen-2021-058180 PMC 바로가기
Sensitive Serology Measurements in the Saliva of Individuals with COVID-19 Symptoms Using a Multiplexed ImmunoassayArticle Published on 2022-10-292022-11-15 Journal: The journal of applied laboratory medicine [Category] COVID19(2023년), SARS, 진단, 치료기술, [키워드] acute respiratory syndrome Antigen benefit causative pathogen collected controls coronavirus coronavirus disease COVID-19 cut-off detect Diagnosis domain group IgG individual individuals with COVID-19 infected individual infected individuals levels of antibody measurement multiplex serology multiplexed immunoassay N-terminal domain nucleocapsid nucleocapsid protein PSO Receptor-binding domain ROC ROC AUC Saliva salivary SARS-CoV-2 sensitive sensitivity Seroconversion serology specificity subjects uninfected uninfected control with COVID-19 [DOI] 10.1093/jalm/jfac073 PMC 바로가기